EstroGel-Estradiol Gel for Estrogen Replacement Therapy
 
EstroGel-Estradiol Gel for Estrogen Replacement Therapy
EstroGel-Estradiol Gel for Estrogen Replacement Therapy Evolution of Estrogen Therapy
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Natural menopause
Menopause is a part of life. It is brought on by a decrease in the production of hormones, such as estrogen. Eventually a woman experiences her last menstrual period. Natural menopause is complete 1 year after the final period.

For some women, menopause symptoms begin several years before their final period. During this transition, hormone levels in a woman’s reproductive system are constantly changing. This natural fluctuation is what causes menopause symptoms.

The symptoms and age at which natural menopause occurs is as different as each woman. On average, a woman may experience menopause anywhere from her 40s to mid-50s. Three to 5 years before menopause, a woman may begin to experience menopause symptoms such as irregularity in her periods, hot flashes, night sweats, and vaginal irritation.

Surgical menopause
There is another type of menopause called surgical menopause. Surgical menopause occurs as a result of a woman having a hysterectomy. A hysterectomy is the surgical removal of all or part of a woman’s reproductive system. If the hysterectomy involves removal of the ovaries (ovaries help produce hormones in women), the woman will experience surgical menopause symptoms due to an abrupt interruption in the amount of hormones produced in her body.

Surgical menopause symptoms generally occur within a few days of surgery and are more frequent, longer in duration, and more severe than symptoms experienced in natural menopause.

Menopause management
If you’re experiencing menopause symptoms, don’t worry. Most symptoms can be managed effectively with estrogen replacement therapies like EstroGel—the first FDA-approved transdermal estrogen gel therapy in the U.S. EstroGel is a convenient, bio-identical estrogen replacement therapy that is an ideal choice for women with active lifestyles.1 Bio-identical means that estradiol, the active ingredient in EstroGel, is similar to the estrogen produced by your body.1,2 EstroGel is a modern option for managing menopause symptoms, such as hot flashes and vaginal dryness and itching.1

While estrogen replacement therapy can help alleviate symptoms, the best way to make the transition as smooth as possible is to know what to expect from menopause. There are plenty of educational resources available to you.

 
 

IMPORTANT SAFETY INFORMATION

EstroGel is indicated in the treatment of moderate to severe vasomotor symptoms associated with menopause and in the treatment of moderate to severe symptoms of vulvar and vaginal atrophy associated with menopause. When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered.

Estrogens increase the chances of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using EstroGel. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find the cause.

Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots.

Do not use estrogens with or without progestins to prevent dementia. Using estrogens with or without progestins may increase your risk of dementia.

EstroGel should not be used if you have unusual vaginal bleeding, currently have or have had certain cancers, had a stroke or heart attack in the past year, currently have or have had blood clots, currently have or have had liver problems, are allergic to EstroGel or any of its ingredients, think you may be pregnant, or if you are breastfeeding.

The most commonly reported adverse events of estrogens include headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps, bloating, nausea and vomiting, and hair loss.

You and your healthcare provider should talk regularly about whether you still need treatment with EstroGel.

Please see full patient information (PDF).

REFERENCES: 1.
EstroGel 0.06% [package insert]. Herndon, VA: ASCEND Therapeutics, Inc; 2006. 2. Boothby LA, Doering PL, Kipersztok S. Bioidentical hormone therapy: a review. Menopause. 2004;11:356-367.

This web site is intended for U.S. residents only.
EstroGel® is a registered trademark of LaSalle Laboratories, Inc. ©2007 ASCEND Therapeutics, Inc. All Rights Reserved.

 
     
   
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